0059 Oncotype Dx, St. Gallen risk group and Adjuvantlonline nomogram as prognostic predictor
نویسندگان
چکیده
منابع مشابه
Oncotype DX: Scientific Publications and Presentations
403 Assay result variability during determination of mismatch repair deficiency status using immunohistochemistry: A transatlantic comparative study. Hutchins G., Gray G., Quirke P. Abstract #491 Use of a multigene prognostic assay for selection of adjuvant chemotherapy in patients with stage II colon cancer: Impact on qualityadjusted life expectancy and costs. Meropol N.J., Lyman G.H., Chien R...
متن کاملOncotype Dx Results in Multiple Primary Breast Cancers
PURPOSE To determine whether multiple primary breast cancers have similar genetic profiles, specifically Oncotype Dx Recurrence Scores, and whether obtaining Oncotype Dx on each primary breast cancer affects chemotherapy recommendations. METHODS A database of patients with hormone receptor-positive, lymph node-negative, breast cancer was created for those tumors that were sent for Oncotype Dx...
متن کاملThe analytical validation of the Oncotype DX Recurrence Score assay
In vitro diagnostic multivariate index assays are highly complex molecular assays that can provide clinically actionable information regarding the underlying tumour biology and facilitate personalised treatment. These assays are only useful in clinical practice if all of the following are established: analytical validation (i.e., how accurately/reliably the assay measures the molecular characte...
متن کاملLow utility of Oncotype DX® in the clinic
Precision medicine tools are currently making their way into the clinic and being utilized to diagnose, prognose, and individualize cancer care. The multi-gene expression-based assay, Oncotype DX® (ODX), is a genomic tumor profiling tool that determines the expression of 21 tumor- associated genes; it helps determine the risk for distant recurrence and whether chemotherapy is an appropriate cou...
متن کاملComparison between Oncotype DX test and standard prognostic criteria in estrogen receptor positive early-stage breast cancer Comparação entre o teste Oncotype DX e critérios prognósticos padronizados em câncer de mama receptor de estrogênio positivo em estágio inicial
Objective: To compare the prognosis estimated by standard prognostic criteria versus the prognosis estimated by the Oncotype DX. Methods: A retrospective study was performed on 22 patients with positive estrogen receptor, early-stage breast cancer who had an Oncotype DX recurrence score available. Results: Kappa value between Oncotype DX and standard prognostic criteria was: Adjuvant! (K = 0.09...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: The Breast
سال: 2009
ISSN: 0960-9776
DOI: 10.1016/s0960-9776(09)70104-3